Try £3

Fleming was not only a Nobel prize-winning scientific mind, but he also had a real appreciation of art. Quite a capable artist himself, having a watercolour hung by the Royal Society of British Water Colour Artists, Fleming also experimented in the lab with pigment-producing microbes. Culturing these colour-producing micro-organisms on Petri dishes, Fleming created a range of images, from boxers in a ring to a mother bottle-feeding a baby. This required not only manual dexterity but the balancing of the growth of several micro-organisms to produce the right pigment, in the right quantity and place, at the right time. 

Nobel Prize laureates of 1945. From left Artturi Virtanen, Chemistry, Alexander Fleming, Medicine, Ernst B Chain, Medicine, Gabriela Mistral, Literature and Howard Florey, Medicine.

Sir Alexander Fleming Scottish biologist and pharmacologist (1881-1955) at St Mary's Hospital, Paddington,London.

Sir Alexander Fleming chaired as the newly-appointed Vice Chancellor of Edinburgh University in 1952

These renderings didn’t necessarily appeal to everyone, however. Allison recalls that Queen Mary, grandmother to the current Queen Elizabeth II, “was not amused and hurried past” when shown these works1. Nonetheless, this art survived, with examples of these bacterial paintings still possible to be seen at the Alexander Fleming Museum at St. Mary’s hospital in London.

Perhaps the most interesting anecdote relating to Fleming’s eye for art is that of VD Allison’s purchase of three etchings at a Sotheby’s auction. Following Fleming’s suggestion to “Try £3”, Allison won the lot, taking home a small collection of works of the then-unknown, Pablo Picasso. He was later able to sell these, as we would expect, for, “a considerable profit.”  

From 3p for tears to £3 for Picassos; Fleming’s eye and contributions had an immeasurable impact on medicine and science in the 20th century. For this, he was knighted in 1944 and co-awarded the Nobel Prize for Physiology or Medicine in 1945. To conclude our first instalment, we leave you with part of his acceptance speech2


  “For many years I have read of people getting the Nobel Prize. Then I always regarded them as a superior class to which it was almost impossible to aspire. Now suddenly I find myself in that class and I wonder whether they are so different. Did they obtain this great distinction – for indeed it is the greatest distinction a scientist can obtain – by deep thought or did Dame Fortune play a part. We all know that chance, fortune, fate or destiny – call it what you will have played a considerable part in many of the great discoveries in science. We do not know how many, for all scientists who have hit on something new have not disclosed exactly how it happened. We do know, though, that in many cases it was a chance observation which took them on a track which eventually led to a real advance in knowledge or practice. This is especially true of the biological sciences for there we are dealing with living mechanisms about which there are enormous gaps in our knowledge”. 

A tradition of innovation

In our next instalment, we will examine the history of lysozyme at Bioseutica Group®, sharing our part in this 100-year story. Join us then.


100 years of Lysozyme

2022 marks 100 years since news of Lysozyme’s discovery reached the Royal Society. Let us take you on the journey of this 100-years story:

100 years of Lysozyme | Episode III Instalment 3

Lysozyme leads the way for DeepMind’s AlphaFold

Lysozyme contributed directly to our understanding of the structure-function relationship of proteins. It was the first solved structure that established the concept that the 3D shape of a  protein[...]

100 years of Lysozyme | Episode I Instalment 1

A beginning for Lysozyme

Bioseutica® group has been producing lysozyme from hen egg-white since the 1950s, a history spanning nearly 75 years. But lysozyme’s story doesn’t begin with us. For that, we must look back to the earliest human use of egg-white[...]

100 years of Lysozyme | Episode I Instalment 2

Thus ended collection of tears

The second instalment of our 100 Years of Lysozyme series is now live. This week we discover how the abundance of Lysozyme in eggs was first discovered (hint: it wasn’t in the supermarket)[...]

100 years of Lysozyme | Episode I Instalment 3

Not a great lecturer

Fleming’s shyness, his being, “not a great lecturer” as acknowledged by Allison, may in part account for the poor reception received at the first reading of the initial paper describing lysozyme[...]

100 years of Lysozyme | Episode I Instalment 4

Try £ 3

From 3p for tears to £3 for Picassos; in this instalment, we uncover how Alexander Fleming’s eye and contributions had an immeasurable impact on medicine and science in the 20th century[...]

100 years of Lysozyme | Episode II Instalment 1

A Tradition of Innovation

The aftermath of the war has left Italy economically devastated like the rest of the European countries. In Milan another Ferrari begins production, but this time of Penicillin.[...]

100 years of Lysozyme | Episode II Instalment 2

A Tradition of Innovation 2

The death of their first trial patient through the insufficient supply of Penicillin drove Florey, Chain, and their research assistant Heatley, forward with inspired momentum.[...]

100 years of Lysozyme | Episode II Instalment 3

A Tradition of Innovation 3

24th May 1947 saw the establishment of SPA (Società Prodotti Antibiotici) by Pharmacologist Dr. Rodolfo Ferrari and microbiologist Carlo Callerio. Now Italy had its own, domestic Penicillin[...]

100 years of Lysozyme | Episode III Instalment 1

More than an antimicrobial

To most of us, if at least those reading, I hope, Lysozyme is best known as a potent, natural antimicrobial. This is evidently its primary purpose for the hen's egg, making[...]

100 years of Lysozyme | Episode III Instalment 2

Finding the structure

Sir. William Bragg and Sir. Lawrence Bragg shared the Nobel Prize in 1915 for their work on analysing crystal structures using X-Rays. This award is notable not only as it was the first and [...]