Pancreatic Enzymes

Neova Technologies Inc., a Bioseutica Group company, produces enzymes extracted from government-certified pork pancreas glands. These pancreas enzymes are naturally occurring pancreatic proteins that play an essential role in the digestion of food. The pancreas enzyme preparation consists of two main enzymes, trypsin and chymotrypsin, blended with an approved excipient to meet different functional requirements determined in consultation with customers.  A third enzyme offered is phospholipase A2 (PA2).  Neova Technologies Inc. is one of the world`s largest manufacturers of porcine-derived enzymes and has been active in the pancreatic enzyme market for over twenty-five years. Products include trypsin/chymotrypsin preparations and phospholipase A2. Market sectors include food, technical, nutraceuticals, and pharmaceuticals.

Trypsin and Chymotrypsin are classified as serine proteases with specific cleaving characteristics.  Trypsin preferentially hydrolyzes bonds whose carboxyl groups are contributed by lysine (Lys) or arginine (Arg). Chymotrypsin hydrolyzes peptide bonds involving phenylalanine (Phe), tyrosine (Tyr), and tryptophan (Try). Phospholipase (PA2) is a standardized product that cleaves the fatty acid in the second position in phospholipids. Pancreatic enzymes effectively hydrolyze a variety of proteins and lipids, using the same natural process as the human digestive system

These preparations are widely utilized in food processing, dietary supplements, infant formula, and pharmaceutical products:

  • for the manufacture of protein hydrolysates;
  • in the extraction of seasonings and flavorings from vegetable or animal proteins;
  • in the manufacture of sauces;
  • to control aroma formation in cheese and milk products;
  • to improve the texture of fish products;
  • to tenderize the meat;
  • during cold stabilization of beer;
  • in the production of hypoallergenic food.
  • in the development of vaccines
  • enzymes for pancreatitis

Pancreatic enzymes product line:

AQUATRYP™

AquaTryp™ is our ready-to-use gentle enzymatic cell detachment reagent. A non-mammalian, non-microbial enzyme mixture, AquaTryp™, can be readily incorporated into most routine cell culture protocols. With predominantly trypsin enzymatic activity, AquaTryp’s enzyme profile makes it an excellent alternative to mammalian and microbial trypsin for most applications.

PHOSPHOLIPASE A2
PHOSPHOLIPASE A2 (PA2) is an enzyme derived from porcine pancreas. It serves as a catalyst in the hydrolysis of the fatty acid in the second position of phospholipids/lecithin.
TRYPSIN 1:250
Trypsin is a pancreatic enzyme used extensively in tissue dissociation, cell harvesting, and microbiological media. Trypsin 1:250 is a trypsin preparation, derived from porcine pancreas, specifically designed as a low endotoxin material for cell culture applications.
TRYPSIN I
TRYPSIN I is our highest purity, most concentrated trypsin preparation, meeting the requirements of both the United States Pharmacopoeia (USP), and the European Pharmacopoeia (EP).
TRYPSIN IV
TRYPSIN IV is a trypsin preparation specifically designed as a low endotoxin material for cell culture applications which can be standardized to a desired trypsin activity.
TRYPSIN SE (Pancreatin)
TRYPSIN SE is a protease complex, containing trypsin (EC 3.4.2 1.4), chymotrypsin (EC 3.4.21.1), pancreatic elastase (EC 3.4.21.36) and carboxypeptidase B (EC 3.4.17.2), obtained from porcine pancreas
TRYPSIN VI
TRYPSIN VI is an enzyme preparation containing both trypsin and chymotrypsin specifically designed for food and nutraceutical applications including infant and follow-on formulae or baby-food.