The natural ingredient to help mood

Bioseutica’s goal is to get people to live good and feel better every day. We are committed to improving the health and well-being of people worldwide by manufacturing high-quality ingredients. All humans strive to live healthy and happy lives, but challenges and anxiety can often get in the way. Mental well-being is strongly linked with physical health. NA2R®, a unique source of tryptophan, has been developed to help positive mood, support mental energy, and a healthy emotional state. We are dedicated to delivering natural nutritional ingredients that contribute to nourishing the brain. NA2R® is a natural ingredient for the novel food/nootropics supplement industry.

NA2R® is a clinically proven natural ingredient for the novel food/nootropics industry. Its daily consumption leads to increased brain serotonin levels, exerting physiologically beneficial effects on brain functions like the mood that, in turn, could promote the feeling of well-being, particularly during stressful times, as well as help emotional and cognitive functions.

Market Applications

  • Food and confectionery industry
  • Beverage companies
  • Dietary supplements producers
  • Nootropic and novel food companies
  • Nutraceutical companies
  • Food 4 thought products

NA2R®: Mental and Physical Sensation Scale

NA2R® consumption reduces responses during reward anticipation in the dorsal caudate nucleus and lifts mood by affecting mood-regulating neurocircuits and increases neural response in the dorsal cingulate cortex during fear processing or threat of shock & increases ventromedial prefrontal lateral connectivity under resting state. Source: Kroes M.C et al, 2014, Neuroimage. 2014 Jan 1;84:825-32. DOI: 10.1016/j.neuroimage.2013.09.041. Epub 2013 Sep 25

Product Overview :

NA2R® is a natural ingredient, made from egg white protein, with a superior amino acid composition which nourishes the brain. NA2R® can thus increase brain serotonin synthesis and improve cognitive function, mood, and emotional processing. The ingredient can be used in beverages, food, dietary supplements, and smart drugs. We are looking for partners to collaborate to establish a final consumer product.

Promotes Focus and Mental Energy :

Clinical data demonstrated that NA2R® improves working memory and increases alertness and reactivity to process information more efficiently (in-house data available).

Balances Mood :

NA2R® nourishes the brain helping to support a positive mood. NA2R® helps to increase levels of a  chemical messenger called serotonin in the brain, which helps control emotions, cognition, and promotes a positive mood.

By helping healthy emotional state NA2R® can aid to improve social life as it has been clinically proven to support the processing of positive emotional bias (in-house data available).

Promotes Wellness :

NA2R® helps support energy which may, in turn, helps to keep you motivated and follow a healthier lifestyle. NA2R® is a natural ingredient that anticipated for a better quality of sleep experience (in-house data available).

Targeting :

NA2R® is a custom ingredient specifically designed for women and athletes as well as to help gamers and coders in their daily challenges providing a stable mood and enhancing focus, working memory and alertness

Product Formulation Plus

The clinical trials and the regulatory approval of the product bring a unique edge in the highly competitive dietary supplements market.

Patented Technology Ingredient 

Patented technology to enhance increased uptake of bioactive tryptophan into the brain.

Natural & cost-effective

NA2R® is an egg white lysozyme hydrolysate, with a superior amino acid composition and cost-effective in low dosage use.

Clinically proven

Effectiveness of the claims and the product safety proven with clinical trials.

Regulatory Compliance

Manufacturer reliability is ensured by HACCP quality.

Bioseutica® NA2R®


Regulatory Status

  • EU: Approved as Novel Food Ingredient 18+: European approval as Novel Food in food supplements intended for adults
  • USA: Approved as a new dietary ingredient (NDI): NA2R® is an FDA  New dietary ingredient (NDI)
  • USA: approved as GRAS

Doping Free:

Qualified as non-doping by The Netherlands Security System Nutritional Supplements Elite Sports (NZVT).
Not included in the WHO/WADA Prohibited doping list


This webpage is not intended for final consumers or to mass caterers: it contains scientific and technical information for "business to business" use only and, therefore, it is directed to food and/or food supplements business operators only. It provides general information and does not constitute medical advice, diagnosis, or treatment. The reader shall be solely responsible for any interpretation or use of the material contained herein. The content of this page is subject to change without prior notice.  Country or region-specific information and regulatory requirements should be considered when labelling or advertising to final consumers. All trademarks listed on this web page are either registered trademarks or trademarks of Bioseutica BV group and cannot be used without expressed written consent of Bioseutica BV.
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